As a young artist in Berkeley during the 1960 and ’70s, Lynn Hershman Leeson’s involvement with issues of civil rights, community, and the conditions for defining a public—most notably through the Floating Museum, 1974–78—helped ground her political and social consciousness. The “museum” platform pooled community resources to commission and exhibit site-specific art in public spaces, first in the San Francisco Bay Area and then more widely in the United States, Italy, and France. She has since spent her career collaborating with scientists and technologists to challenge how we construct identity and understand the body’s relation to its environment. Below, the artist discusses how her work with antibodies and DNA as part of Infinity Engine, 2014–, relates to strategies for surviving Covid-19.